AIDS Inc. is mainly based around the Duesberg risk-group theory which says HIV doesn't cause AIDS, rather, AIDS is caused by a general weakening of the immune system due to drug abuse, disease, parasites, malnutrition, etc. The film explores the first 2 major outbreaks in the early 80's and whether the explosion of HIV on the US Gay scene was due to drugs & lifestyle, and if the epidemic in Africa is actually the same diseases that have been killing Africans for many centuries, but are just now all being labelled as AIDS to keep the massive HIV Pharmaceutical industry alive, as President Mbeki of South Africa openly believes himself.